The festivities are in honour of Lydia Dingle's (Karen Blick) birthday, but it's fair to say all eyes won't be on her!
So, while we wait for all the drama to unfold, let's delve into all the characters with a grudge to bear against devious Joe.
Read on below as we weigh up all the options ahead of Joe's shocking downfall.
Noah Dingle
Noah struggles to come to terms with what he's found out, knowing that Joe drugging him caused the deaths of Suzy Merton (Martelle Edinborough), Leyla Harding (Roxy Shahidi) and Amy Barton (Natalie Ann Jamieson), when a disoriented Noah stumbled into the path of the limousine driven by Charity.
Noah has been feeling the weight of the tragic events, but could this push him to take action against his half-brother?
Kerry Wyatt
Official spoilers have revealed that Kerry's fury will be evident when she realises that Joe is to blame for what happened.
Will the ever-impulsive Kerry take matters into her own hands? It's as likely as any other possibility.
Cain Dingle
It was Cain who orchestrated the uneasy truce between Joe and Caleb (William Ash), wanting to stop Caleb from making a big mistake after the latter tried to mow Joe down over the kidney theft.
After decades of punch-ups, locking people in car boots and tying them up in barns, would it be too predictable for Cain to hit out at Joe this time? Or will something reignite Cain's anger?
Ruby Miligan
After all, with Joe's knowledge of her father Anthony's (Nicholas Day) murder keeping her and husband Caleb from seeking vengeance, would Ruby risk her own freedom just to hurt Joe?
However, Joe has been very interested in Steph's troubling behaviour of late, and if he pushes too hard, even after promising to stay away from the Miligans, could we see lioness Ruby's maternal instincts kicking in for Steph's sake?
Caleb Miligan
But Caleb is seen at the party staring daggers Joe's way, so perhaps his anger over kidney-gate will get the better of him, despite all that's at stake?
Will Caleb jeopardise their murder cover-up in one moment of rage?
Charity Dingle
Now, she's ready and raring to go on a big scheme to destroy Joe, and this makes her a leading suspect in our eyes.
Is sending Joe through a window her goal, or does she have something else in mind, only for another of Joe's rivals to get there first?
Billy Fletcher
Caleb spurs Billy on to go after Joe, but will he really turn to violence to make him pay?
Billy is watching Joe closely at Home Farm, but will he be pushed t0 the edge?
Dawn Fletcher
So, if Dawn found out what Joe did to Clemmie, would she see red and send him flying?
The point is, Dawn has it in her to endanger life – so will Joe pay the price for scaring Clemmie?
Clemmie Reed
But even if she wanted to hurt Joe, would Clemmie be capable of shoving him so hard he fell through a window?
But it's a very dark story to give the vulnerable Clemmie, so we'll just have to wait and see whether Emmerdale takes this route.
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Emmerdale airs Mondays to Fridays at 7:30pm on ITV1. Stream on ITVX.
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