Drug discovery study identifies promising new compound to open constricted airways ...Middle East

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Drug discovery study identifies promising new compound to open constricted airways
source : ( Middle East ) () 8
In a preclinical study led by the University of South Florida, researchers identified and characterized 18 new compounds (agonists) that activate bitter taste receptor subtype TAS2R5 to promote relaxation of human airway smooth muscle cells. The cross-disciplinary team found 1,10 phenanthroline-5,6-dione (T5-8 for short) was 1,000 times more potent than some of the other bronchodilator agonists tested, and it demonstrated marked effectiveness in human airway smooth muscle cells grown in the laboratory.

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