Another blowout loss leaves the Niners in last place in the NFC West.

Josh Allen and the Bills will welcome the reigning NFC champion San Francisco 49ers with some wintry Buffalo weather for Sunday Night Footba...

Tampa Bay Buccaneers running back Bucky Irving runs for a touchdown against the Carolina Panthers. (AP Photo/Jacob Kupferman) When the Tampa...

Sam Darnold led the Vikings on a late game-winning drive to fend off the Cardinals on Sunday afternoon. (AP/Stacy Bengs) It took Sam Darnold...

ATLANTA — The Atlanta Falcons ought to have locked down the NFC South by now, but the Falcons continue to demonstrate that they’re their own...

On Sunday, the New York Jets meet the Seattle Seahawks in an exciting NFL showdown between AFC and NFC foes.

ORCHARD PARK, N.Y. (AP) — Running back Christian McCaffrey refuses to buy into the doom and gloom surrounding the San Francisco 49ers since...

Week 13 of the NFL season is in full swing following four games on Thanksgiving and Black Friday. The Detroit Lions survived a thrilling sec...

Yet on Sunday night in frigid Orchard Park, the 49ers, mired at 5-6 and a game out of first place in the NFC West, find their season hanging...

Former Chicago Bears head coach Matt Eberflus issued a statement Saturday after his historic firing, which came on the heels of a gut-...

Running back Christian McCaffrey says the San Francisco 49ers are "hungry" to make a playoff push even with the defending NFC champions sit...

MICHAEL Strahan leaped to the defence of Jimmy Johnson after an appare...

Mismanagement of final drive vs. Lions on Thanksgiving led to the decision.

Mismanagement of final drive vs. Lions on Thanksgiving led to the decision.

Los Angeles Chargers (7-4) at Atlanta Falcons (6-5), 1 p.m. ET, FOX,Atlanta holds a one-game lead over the Tampa Bay Buccaneers in the NFC...