Liverpool will host Southampton at Anfield in a Premier League clash that presents an intriguing contrast between the two teams' current trajectories. Liverpool, sitting comfortably at the top of the league with a 13-point lead, comes off a recent Champions League victory against PSG, while Southampton languishes at the bottom of the table with only one away win in their last 21 matches . This match is particularly significant for Liverpool as they aim to extend their lead to an impressive 16 points.
Liverpool were given their toughest assignment of the season on Wednesday evening as they travelled to Paris Saint-Germain in the first leg of their Champions League last 16 tie. The French side were utterly dominant throughout a difficult evening for Arne Slot's side, but Harvey Elliott's late effort secured a significant win ahead of this Tuesday's return leg.
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Southampton are unlikely to pose even a tenth of the challenge that PSG offered midweek, with Ivan Juric having been unable to rescue their fortunes. The Croatian has lost ten of his 12 matches since taking charge, with the south coast side now sat 13 points from safety. They are yet to reach double digits in the Premier League.
Two sides at completely opposite ends of the Premier League standings will meet this weekend when Liverpool take on Southampton at Anfield on Saturday afternoon. The Reds are perched 13 points clear at the summit of the league standings, while the Saints are the basement club, 13 points from safety. Check out our match prediction below!
Liverpool have been the better team by some distance in this contest, winning all but two of their last 13 matches against this opponent, with the exceptions being a 1-0 defeat in 2021 and a thrilling 4-4 draw in 2023. Southampton have failed to win any of their last nine Premier League visits to Anfield, losing seven and drawing twice, while being outscored 19-1 over that period. 
Liverpool possible starting lineup: Alisson; Alexander-Arnold, Quansah, Van Dijk, Tsimikas; Gravenberch, Jones; Salah, Elliott, Diaz; Nunez
Southampton possible starting lineup: Ramsdale; Sugawara, Harwood-Bellis, Bednarek, Bella-Kotchap, Walker-Peters; Fernandes, Ugochukwu, Smallbone, Sulemana; Onuachu
Despite some potential rotation in Liverpool's lineup due to their midweek exertions, they are expected to field a strong team. Predicted formations suggest a 4-2-3-1 setup featuring Alisson in goal and key players such as Salah and Nunez leading the attack . Conversely, Southampton's lineup remains less predictable but may include Kamaldeen Sulemana and Paul Onuachu upfront. The lack of television coverage in the UK has drawn attention to alternative broadcasting options like BBC Radio 5 Live for commentary.
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