A case of the clade 1b variant was confirmed in the western Brittany region and “the recommended oversight measures have been implemented”, the ministry said in a statement.
It causes fever, muscular aches and large boil-like skin lesions, and can be deadly.
The WHO declared an emergency over the virus in August and renewed it on November 22 following an outbreak in the Democratic Republic of Congo (DRC).
“However this person was in contact with two people who returned from central Africa. Inquiries are underway to find the origin of the infection and identify all people in contact.”
The agency has warned European nations to be prepared for “rapid action” to contain the latest variant.
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