Eli Lilly, the pharmaceutical company behind the injectable diabetes drug Mounjaro and the weight loss injection Zepbound, announced that in clinical trials, their oral GLP-1 called orforglipron demonstrated results nearly on par with its injectable predecessors. That said, there are important details to note here before you get too excited about a quick fix to slim down for bikini season.
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First, there are some benefits to GLP-1s in pill form that may make it affordable—so that's good news.
The downside? "There is currently no oral GLP1 FDA approved for weight loss (Rybelsus is approved for diabetes), and it seems to be less effective [for diabetes]."
Are GLP-1 Medications the Most Effective Medical Intervention for Weight Loss?
Whether it's in pill or injectable form, Dr. Ali says that GLP-1s are a good option for many, but not necessarily the best option for most people looking to lose weight and overcome obesity.
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What Are the Side Effects of GLP-1 Medications?
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"If patients do not make significant, long-term dietary and lifestyle changes, it is very easy to regain weight after stopping the medications," Dr. Ali warns.
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Sources
Dr. Mir B. Ali, MD"Eli Lilly sues four telehealth sites selling compounded Zepbound, Mounjaro." NBC News."Gastroparesis." Cleveland Clinic."Lilly's oral GLP-1, orforglipron, demonstrated statistically significant efficacy results and a safety profile consistent with injectable GLP-1 medicines in a successful Phase 3 trial." Lilly Investors. Read More Details
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