The standoff took place in the suburb of Paramount, where demonstrators had gathered near a Home Depot that was being used as a staging area by federal immigration officials, the Fox 11 news outlet reported.
The immigration raids are part of US President Donald Trump's ongoing crackdown on undocumented immigrants.
Following the latest clashes in Los Angeles, authorities vowed to prosecute offenders and warned of an escalating security presence.
FBI Deputy Director Dan Bongino said multiple arrests had been made following Friday's clashes.
On Saturday, amid chants for Immigration and Customs Enforcement (ICE) agents to get out, some protestors waved Mexican flags while others set a US flag on fire, the Los Angeles Times said.
A crowd swarmed a US Marshals Service bus exiting a nearby freeway, with authorities later closing on and off ramps to keep protesters from taking over the highway.
“An insurrection against the laws and sovereignty of the United States,“ White House deputy chief of staff and anti-immigration hardliner Stephen Miller said on X, sharing a video of protesters marching Friday outside Los Angeles’s federal detention center.
The suburb of Paramount, home to about 50,000 people, is 82 percent Hispanic or Latino, according to US Census data.
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