Now the show is back, focusing on a new doctor, Dr James Ford, played by Tom Hughes.
Psychiatry was writer Grace Ofori-Attah's speciality when she was a doctor, meaning she had plenty of experience on what to base the series.
Speaking exclusively with RadioTimes.com, Ofori-Attah said: "It's a lot more obvious with an A&E situation where everything just is inherently quick turnover. See a patient, quick, on to the next risk.
"With psychiatry, it's a slow burn. But once something happens, you're off and away, and it's very fast-paced."
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Vera legend confirmed for remake of classic Channel 4 dramaGemma Arterton in first look at Secret Service – starring Doctor Who and Happy Valley actors"Because it's hard to set up for an audience the kind of culture of specialties within the NHS, and that's sort of what we tried to do in the beginning, where you see Dr Ford navigating the final hour or two of his shift, and what to prioritise."
An investigation into his behaviour begins, led by returning characters Dr Norma Callahan and Dr George Adjei of the Medical Investigation Unit.
"You don't get the full tilt straight away," Behan said, "you get drip fed, which is torture, but I very much read it like an audience member.
"So I was kind of finding it out as it was developing, which was thrilling to play."
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