Several people were rescued from rooms and roof of the budget hotel, Kolkata police chief Manoj Verma told AFP, after the fire broke out on Tuesday evening.
“The hotel turned into a gas chamber and it appears that many people suffocated to death.”
About a dozen people suffered burn injuries and were undergoing treatment.
Last year, six people were killed in a fire at a hotel in Patna in the eastern state of Bihar.
Kolkata’s The Telegraph newspaper reported that at least one person died when he “jumped off the terrace trying to escape” the fire.
Prime Minister Narendra Modi offered his condolences to the families of those killed.
Kolkata, a bustling metropolis of more than 15 million people, is the capital of West Bengal state, which is governed by the opposition Trinamool Congress party.
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