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Published in Scientific Reports in March 2025, the study involved 127 cognitively healthy participants, 34 individuals who had noticed changes in their memory (but hadn’t received a diagnosis) and 19 people with mild cognitive impairment (MCI), a clinical condition often considered an early stage of Alzheimer’s disease.
Each participant received a scratch-and-sniff test kit and was asked for odor identification (what smell it was), odor memory (if they had smelled it before or not) and odor discrimination (whether two scents were the same were different). They also ranked how strong each smell was on a scale from zero to 10.
The Connection Between Brain Health and Smell
Finally, participants who had no sense of smell performed at "chance level," or demonstrated that they were guessing at random, confirming the test's accuracy.
“Our goal has been to develop and validate a cost-effective, noninvasive test that can be performed at home, helping to set the stage for advancing research and treatment for Alzheimer’s," he contined. Hopefully, this research will allow them to do just that.
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Related: This Simple Habit May Be Quietly Raising Your Risk of Dementia and Alzheimer’s
Sources
"The AROMHA brain health test is a remote olfactory assessment to screen for cognitive impairment." Scientific Reports."Early detection of Alzheimer's may start with simple test." The Harvard Gazette. Read More Details
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