CDC warns 'slapped cheek' disease on the rise, Human Parvovirus B19

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B19. This viral infection is characterized by its distinctive rash that resembles slapped cheeks, particularly in children. The CDC's alert highlights important public health implications, considering that this disease can lead to various complications, especially in vulnerable populations such as pregnant women and individuals with compromised immune systems or underlying hematological disorders.

Human parvovirus B19 is transmitted through respiratory secretions and has an incubation period of approximately 4 to 14 days. Symptoms often begin with mild fever and flu-like signs before progressing to the hallmark facial rash. Although most cases are self-limiting and resolve without medical intervention, the potential for severe anemia exists in certain demographics, notably among those with sickle cell disease or other forms of chronic hemolytic anemia. Moreover, pregnant women who contract parvovirus B19 face risks associated with fetal hydrops or miscarriage due to the virus's impact on red blood cell production.

B19 is a seasonal respiratory virus that is transmitted through respiratory droplets by people with symptomatic or asymptomatic infection. In the first quarter of 2024, public health authorities in 14 European countries observed unusually high numbers of cases of parvovirus B19. In the United States, there is no routine surveillance for parvovirus B19, and it is not a notifiable condition.

According to Forbes, infections are usually asymptomatic or cause mild, flu-like illness with symptoms like fatigue, headache, muscle aches, and fever, with many going on to experience a second stage of illness with symptoms like a characteristic facial rash, often called a "slapped cheek" rash, followed by joint pain and swelling, and a general body rash.

The disease is also spreading in other parts of the world. In the first quarter of 2024, public health authorities in 14 European countries observed unusually high numbers of cases of parvovirus B19.

Many people who contract parvovirus B19 are asymptomatic, but children and adults with symptoms usually experience effects in two phases.

In the first phase, when individuals are most contagious, people may experience symptoms of fever, myalgia and malaise that develop about seven days after becoming infected. The first phase lasts about five days.

CDC recommends people take general respiratory precautions, such as covering their mouth and nose when coughing or sneezing, washing their hands properly, cleaning frequently touched surfaces, and possibly donning a mask when around other people, as there are no vaccines to prevent parvovirus B19 infection.

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