Indian scientists ace 1st human clinical trial of haemophilia A gene therapy ...Middle East

New Delhi, Feb 28 (IANS) Scientists at the Christian Medical College (CMC) Vellore have successfully conducted the country’s first human clinical trial of gene therapy for haemophilia A (FVIII deficiency), Union Minister Dr. Jitendra Singh said on Wednesday. He said this while addressing the “National Science Day 2024” programme at Vigyan Bhawan here. Hemophilia A is a genetic disorder caused by missing or defective factor VIII (FVIII), a clotting protein, which means the patient bleeds longer than others. The clinical trials involved deploying a novel technology of using a lentiviral vector to express a FVIII transgene in the patient’s own haematopoietic stem cell, which will then express

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