Despite drop in number of COVID-19 tests, at-home testing is expected to grow -- but experts raise concerns about costs and the reporting of positive results. Medscape Medical News

Investigators identify why hyperactivation of the immune system can wreak more damage than influenza and other coronaviruses in some people with SARS-CoV-2. Medscape Medical News

In a cohort of almost 800 professional athletes with previous COVID infection, routine return-to-play screening showed signs of inflammatory heart disease in only 5. Medscape Medical News

Nearly $200 million has been added to sequencing efforts in the United States as experts monitor mutations and flag major problems from breakthrough infections and other concerns. Medscape Medical News

A former Yale fertility nurse admitted to replacing painkillers with saline, knowing it would cause patients harm. Medscape Medical News

The higher dose remains the standard, but a new ENGAGE AF-TIMI 48 analysis puts the lower dose of the direct oral anticoagulation back in play. Medscape Medical News

Here are five things to know about solriamfetol (Sunosi), the first dual-acting dopamine and norepinephrine reuptake inhibitor for the treatment of persistent daytime sleepiness in adults. Medscape Medical News

The report finds that Rear Adm. Ronny Jackson, MD, created a negative work environment and inappropriately used alcohol. Medscape Medical News

Severe COVID-19 patients have sustained platelet activation, likely contributing to thrombotic issues seen with the infection. Antiplatelet therapy such as aspirin may be of benefit, researchers say. Medscape Medical News

Hundreds of thousands of deaths worldwide from COVID-19 could have been avoided if obesity rates were lower; call for people with obesity to be included in priority lists for COVID-19 vaccination. Medscape Medical News

The CDC is expected to soon release guidelines on safe activities for fully vaccinated people, Politico and other news organizations reported. WebMD Health News

As the speed of COVID vaccinations picks up, so do the reports of doses going to waste. Health officials are trying to rein in waste without slowing down vaccinations. Kaiser Health News

Accelerating time to initiation of antibiotics for patients with sepsis means that patients are treated earlier, but it could result in more patients receiving antibiotics, including those without infection. Medscape Medical News

"The new guidance from the federal government makes it really clear that those federal tests are to be covered without a charge to the patient." Associated Press

The recommendations are based on evidence from six randomised controlled trials involving over 6,000 participants with and without known exposure to a person with COVID-19 infection. Medscape Medical News

In his role as head of the division of pediatric behavioral health at National Jewish Health, Bruce Bender, PhD, helps kids and adults navigate the adverse effects of severe AD on their quality of life. Medscape Medical News

Buoyed by a surge in vaccine shipments, states and cities are rapidly expanding eligibility for COVID-19 shots to teachers, Americans 50 and over and others. Associated Press

The small cell lung cancer (SCLC) indication had been granted an accelerated approval, but a subsequent confirmatory study showed no survival benefit. Medscape Medical News

A study of post–COVID-19 patients in the UK who developed severe lung inflammation after they left the hospital may provide greater clarity on which patients are most likely to have persistent lung dysfunction. Medscape Medical News

An increase in breast cancer mortality among women younger than 40 highlights the value of regular screening, which is not currently recommended for this age group, say researchers. Medscape Medical News

An umbrella review of meta-analyses found convincing evidence that some dietary factors increase the risk for colorectal cancer and that others may lower it. Medscape Medical News

Fears of untoward events after skin testing or oral challenges for penicillin allergy in pregnant women appear to be unfounded. Medscape Medical News

Caution is warranted in making early decisions to withdraw or withhold treatment in comatose patients with TBI as many will regain consciousness in time, new research suggests. Medscape Medical News

A higher rate of conversion to multiple sclerosis in the placebo group offered a glimmer of hope for treatment in TONE, a phase 3 randomized trial, but caveats loom large. Medscape Medical News

After students and alumni called her removal racist and sexist, Princess Dennar, MD, has been offered the chance to return to her role as residency director at Tulane University School of Medicine. Medscape Medical News